Molecular Formula | C13H16F3N5O4S |
Molar Mass | 395.36 |
Density | 1.92±0.1 g/cm3(Predicted) |
Boling Point | 704.3±70.0 °C(Predicted) |
pKa | 13.07±0.70(Predicted) |
Overview | In the field of chemistry, Cangrello (Cangrelor) is an antagonist of non-thienopyridine purine receptor P2Y12, as a rapid-acting intravenous antithrombotic drug for the treatment of acute coronary syndrome. 2-(3,3,3-trifluoropropyl) adenine nucleoside is an important intermediate of Cangrilol, so the synthesis of 2-(3,3,3-trifluoropropyl) adenine nucleoside has always been an important topic in the field of synthetic chemistry. For the synthesis process of trifluoropropyl thioadenosine, there are few reports in the existing technology. The synthesis process involved in a small number of reports is not suitable for industrial production due to harsh synthesis conditions, large equipment investment and high cost. |